Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene.
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Protein Aliases: alpha-2, 8-sialytransferase; alpha-2,8-sialyltransferase; alpha-N-acetylneuraminate: alpha-2,8-sialytransferase; alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; GD3 synthase; sialyltransferase 8 (alpha-2 8-sialytransferase) A; Sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-28-sialytransferase GD3 synthase); Sialyltransferase 8 A (alpha-N-acetylneuraminate: alpha-28-sialytransferase GD3 synthase) GenBank no: U53883
Gene Aliases: Siat8; Siat8a
Entrez Gene ID: (Rat) 25280
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