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This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase; polysialyltransferase; sialyltransf; sialyltransferase 8 (alpha-2 8-polysialyltransferase) D; sialyltransferase 8 (alpha-2 8-polysialytransferase) D; sialyltransferase 8 (alpha-2, 8-polysialyltransferase) D; sialyltransferase 8 (alpha-2, 8-polysialytransferase) D; sialyltransferase 8 (alpha-2, 8-sialytransferase) D
Gene Aliases: Siat8d
Entrez Gene ID: (Rat) 116696
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