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Invitrogen
STAG2 Recombinant Rabbit Monoclonal Antibody (1H3L8)
FIGURE: 1 / 8
STAG2 Antibody (702499) in ICC/IF
Knockdown of STAG2 was achieved by transfecting HeLa cells with STAG2 specific siRNA (Silencer® select Product # s21089). Immunofluorescence analysis was performed on HeLa cells (untransfected, panel a-d), and cells transfected with STAG2 specific siRNA (panel i-l) or non-specific scrambled siRNA (panels e-h). Cells were fixed, permeabilized, and labelled with Anti-STAG2 Recombinant Rabbit Monoclonal Antibody (Product # 702499, 2 µg/mL), followed by Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjug... View More
Product Details
702499
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
1H3L8
Immunogen
Peptides corresponding to human [1) aa1213-aa1231, 2) aa438-aa457]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2688160
Product Specific Information
This antibody is predicted to react with Monkey, Dog, Sheep
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
STAG2 is a component of the cohesin complex. This complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cohesin subunit SA-2; DKFZp686P168; DKFZp781H1753; FLJ25871; OTTHUMP00000024338; OTTHUMP00000043514; OTTHUMP00000043515; OTTHUMP00000081754; OTTHUMP00000081755; RP11-517O1.1; SCC3 homolog 2; Stromal antigen 2
Gene Aliases: bA517O1.1; SA-2; SA2; SCC3B; STAG2
UniProt ID: (Human) Q8N3U4
Entrez Gene ID: (Human) 10735
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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