Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLQINQMFSV QLSLGEQTWE SEGSSIKKAQ QAVANKALTE STLPKPVQKP PKSNVNNNPG SITPTVELNG LAMKRGEPAI YRPLDPKPFP NYRANYNFRG MYNQRYHCPV PKIFYVQLTV GNNEFFGEGK TRQAARHNAA MKALQALQNE PIPERSPQNG ESGKDMDDDK DANKSEISLV FEIALKRNMP VSFEVIKESG PPHMKSFVTR VSVGEFSAEG EGNSKKLSKK RAATTVLQEL KKLPPLPVVE KPKLFFKKRP KTIVKAGPEY GQGMNPISRL AQIQQAKKEK EPDYVLLSER GMPRRREFVM QVKVGNEVAT GTGPNKKIAK KNAAEAMLLQ LGYKASTNLQ DQLEKTGENK GWSGPKPGFP EPTNNTPKGI LHLSPDVYQE MEASRHKVIS GTTLGYLSPK DMNQPSSSFF SISPTSNSSA TIARELLMNG TSSTAEAIGL KGSSPTPPCS PVQPSKQLEY LARIQGFQV
Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48. 5% and 59. 9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Double-stranded RNA-binding protein Staufen homolog 2; staufen homolog 2; staufen, RNA binding protein, homolog 2
Gene Aliases: 39K2; 39K3; STAU2
UniProt ID: (Human) Q9NUL3
Entrez Gene ID: (Human) 27067
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