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Invitrogen
STEAP4 Polyclonal Antibody
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STEAP4 Antibody (PA5-115971) in IHC (P)
Immunohistochemistry analysis of STEAP4 in human Prostate cancer tissue sections. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115971) at a dilution of 1:100. Secondary staining was applied with HRP conjugated goat anti-rabbit.
Product Details
PA5-115971
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human STEAP4(Accession Q687X5), corresponding to amino acid residues L422-H459.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2900605
Product Specific Information
Antibody detects endogenous levels of total STEAP4.
Target Information
The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp666D049; FLJ23153; Metalloreductase STEAP4; six transmembrane prostate protein 2; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STEAP family member 4; Tumor necrosis factor, alpha-induced protein 9; tumor necrosis-alpha-induced adipose-related protein
Gene Aliases: STAMP2; STEAP4; TIARP; TNFAIP9
UniProt ID: (Human) Q687X5
Entrez Gene ID: (Human) 79689
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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