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STRN Polyclonal Antibody

STRN Antibody in Immunocytochemistry (ICC/IF)

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STRN Antibody (21624-1-AP) in ICC/IF

Immunofluorescent analysis of Hela cells, using STRN antibody 21624-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

STRN Antibody in Immunohistochemistry (Paraffin) (IHC (P))

STRN Antibody in Immunoprecipitation (IP)

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Product Details

21624-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2400

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

STRN Fusion Protein Ag15984 (301-403 aa encoded by BC106879)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: NRSKLQDML ANLRDVDELP SLQPSVGSPS RPSSSRLPEH EINRADEVEA LTFPPSSGKS FIMGADEALE SELGLGELAG LTVANEADSL TYDIANNKDA LRKT (301-403 aa encoded by B C106879)

Target Information

Striatin is found in all mammalian cells assayed and may be involved in vesicular transport, dendrite growth, and cellular signaling. It binds Protein phosphatase 2A (PP2A) A and C subunits and calmodulin and appears to modulate PP2A activity. It also binds the human homolog of the yeast protein, Mob1, which has been implicated in mitotic progression in yeast. It is a member of a family of proteins that also includes SG2NA and Zinedin. This antibody does not cross-react with SG2NA.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

CircTNPO3 promotes hepatocellular carcinoma progression by sponging miR-199b-5p and regulating STRN expression.

The Kaohsiung journal of medical sciences

Liu J,Liu B

Wed Mar 01 00:00:00 UTC 2023

Effect of Combined Methamphetamine and Oxycodone Use on the Synaptic Proteome in an In Vitro Model of Polysubstance Use.

Genes

Meyer D,Athota P,Gowen A,Nguyen NM,Schaal VL,Yelamanchili SV,Pendyala G

Sat Oct 08 00:00:00 UTC 2022

High STRN Expression Promotes HCC Invasion and Migration but Not Cell Proliferation or Apoptosis through Facilitating Epithelial-Mesenchymal Transition.

BioMed research international

Du QY,Yao JH,Zhou YC,Xu LJ,Zhao FY,Yang Y

Mon Jan 11 00:00:00 UTC 2021

High STRN Expression Promotes HCC Invasion and Migration but Not Cell Proliferation or Apoptosis through Facilitating Epithelial-Mesenchymal Transition.

BioMed research international

Du QY,Yao JH,Zhou YC,Xu LJ,Zhao FY,Yang Y

Mon Jan 11 00:00:00 UTC 2021

Striatin Is Required for Hearing and Affects Inner Hair Cells and Ribbon Synapses.

Frontiers in cell and developmental biology

Nadar-Ponniah PT,Taiber S,Caspi M,Koffler-Brill T,Dror AA,Siman-Tov R,Rubinstein M,Padmanabhan K,Luxenburg C,Lang RA,Avraham KB,Rosin-Arbesfeld R

Sat Mar 30 00:00:00 UTC 2024

Striatin Is Required for Hearing and Affects Inner Hair Cells and Ribbon Synapses.

Frontiers in cell and developmental biology

Nadar-Ponniah PT,Taiber S,Caspi M,Koffler-Brill T,Dror AA,Siman-Tov R,Rubinstein M,Padmanabhan K,Luxenburg C,Lang RA,Avraham KB,Rosin-Arbesfeld R

Sat Mar 30 00:00:00 UTC 2024

Precise and systematic survey of the efficacy of multicomponent drugs against functional dyspepsia.

Scientific reports

Wei J,Man Q,Guo F,Xian M,Wang T,Tang C,Zhang Y,Li D,Tang D,Yang H,Huang L

Wed Jul 24 00:00:00 UTC 2019

Heavy metal-induced metallothionein expression is regulated by specific protein phosphatase 2A complexes.

The Journal of biological chemistry

Chen L,Ma L,Bai Q,Zhu X,Zhang J,Wei Q,Li D,Gao C,Li J,Zhang Z,Liu C,He Z,Zeng X,Zhang A,Qu W,Zhuang Z,Chen W,Xiao Y

Fri Aug 08 00:00:00 UTC 2014

Heavy metal-induced metallothionein expression is regulated by specific protein phosphatase 2A complexes.

The Journal of biological chemistry

Chen L,Ma L,Bai Q,Zhu X,Zhang J,Wei Q,Li D,Gao C,Li J,Zhang Z,Liu C,He Z,Zeng X,Zhang A,Qu W,Zhuang Z,Chen W,Xiao Y

Fri Aug 08 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: protein phosphatase 2 regulatory subunit B'''alpha; Striatin; striatin, calmodulin binding protein; striatin, calmodulin-binding protein

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Gene Aliases: AU022939; D130055P19; PPP2R6A; SG2NA; STRN

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UniProt ID: (Human) O43815, (Mouse) O55106, (Rat) P70483

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Entrez Gene ID: (Human) 6801, (Mouse) 268980, (Rat) 29149

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Function(s)

protein binding calmodulin binding estrogen receptor binding protein complex binding protein phosphatase 2A binding armadillo repeat domain binding protein domain specific binding calcium-dependent protein binding

Process(es)

locomotory behavior negative regulation of cell proliferation Wnt signaling pathway dendrite development bicellular tight junction assembly

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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STRN Polyclonal Antibody

STRN Antibody (21624-1-AP) in ICC/IF

Product Details

21624-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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