Search Thermo Fisher Scientific
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Invitrogen
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Immunogen sequence: YEPNVLAGTL VGHTDAVWGL AYSGIKNQLL SCSADGTVRL WNPQEKLPCI CTYNGDKKHG IPTSVDFIGC DPAHMVTSFN TGSAVIYDLE TSQSLVILSS QVDSGLQSNN HINRVVSHPT LPVTITAHED RHIKFFDNKT GKMI
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.
SG2NA was identified as a human cancer autoantigen and has now been implicated in vesicular trafficking and signal transduction. It is highly related to striatin and zinedin. It is a scaffolding protein that binds PP2A A and C subunits as well as the human homolog of the yeast protein, Mob1, which has been implicated in control of mitotic progression in yeast. It also binds calmodulin and appears to modulate PP2A activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cell cycle autoantigen SG2NA; cell cycle S/G2 nuclear autoantigen; nuclear autoantigen; protein phosphatase 2 regulatory subunit B'''beta; S/G2 antigen; striatin, calmodulin binding protein 3; Striatin-3
Gene Aliases: GS2NA; PPP2R6B; SG2NA; STRN3
UniProt ID: (Human) Q13033
Entrez Gene ID: (Human) 29966
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