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Product Details
PA5-88640
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 200-460 of human STRN3 (NP_0010773621)
Conjugate
Form
Liquid
Concentration
0.55 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805046
Product Specific Information
Immunogen sequence: VRSLLGLSNS EPNGSVETKN LEQILNGGES PKQKGQEIKR SSGDVLETFN FLENADDSDE DEENDMIEGI PEGKDKHRMN KHKIGNEGLA ADLTDDPDTE EALKEFDFLV TAEDGEGAGE ARSSGDGTEW DKDDLSPTAE VWDVDQGLIS KLKEQYKKER KGKKGVKRAN RTKLYDMIAD LGDDELPHIP SGIINQSRSA STRMTDHEGA RAEEAEPITF PSGGGKSFIM GSDDVLLSVL GLGDLADLTV TNDADYSYDL P; Positive Samples: Mouse brain; Cellular Location: Cytoplasm, Membrane, Peripheral membrane protein
Target Information
SG2NA was identified as a human cancer autoantigen and has now been implicated in vesicular trafficking and signal transduction. It is highly related to striatin and zinedin. It is a scaffolding protein that binds PP2A A and C subunits as well as the human homolog of the yeast protein, Mob1, which has been implicated in control of mitotic progression in yeast. It also binds calmodulin and appears to modulate PP2A activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell cycle autoantigen SG2NA; cell cycle S/G2 nuclear autoantigen; nuclear autoantigen; protein phosphatase 2 regulatory subunit B'''beta; S/G2 antigen; SG2NA beta isoform; striatin, calmodulin binding protein 3; Striatin-3; striatin-3 35 kDa
Gene Aliases: GS2NA; PPP2R6B; SG2NA; STRN3
UniProt ID: (Human) Q13033, (Mouse) Q9ERG2
Entrez Gene ID: (Human) 29966, (Mouse) 94186
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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