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Immunogen sequence: YEIIQQPMSY DNLTQRLTVE AAQFIQRNTE TPFLLVLSYL HVHTALFSSK DFAGKSQHGV YGDAVEEMDW SVGQILNLLD ELRLANDTLI YFTSDQGAHV EEVSSKGEIH GGSNGIY
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI).
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Protein Aliases: Arylsulfatase C; ASC; Estrone sulfatase; Steroid sulfatase; Steryl-sulfatase; Steryl-sulfate sulfohydrolase
Gene Aliases: ARSC; ARSC1; ASC; ES; SSDD; STS; XLI
UniProt ID: (Human) P08842
Entrez Gene ID: (Human) 412
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