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OriGene
STX18 Monoclonal Antibody (OTI2B5), TrueMAB™
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FIGURE: 1 / 2
STX18 Antibody (CF809423) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY STX18 (RC201016, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-STX18. Positive lysates LY413750 (100 µg) and LC413750 (20 µg) can be purchased separately from OriGene.
Product Details
CF809423
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2B5
Immunogen
Human recombinant protein fragment corresponding to amino acids 1-285 of human STX18 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Syntaxin 18 mainly localizes to the endoplasmic reticulum (ER), and functions in transport between the ER and Golgi. Syntaxin 18 also plays a role in ER-mediated phagocytosis, possibly by regulating the specific fusion of the ER and plasma or phagosomal membranes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell growth-inhibiting gene 9 protein; Syntaxin-18
Gene Aliases: 1810035L21Rik; 4933425D03Rik; AU041562; GIG9; STX18; Ufe1
UniProt ID: (Human) Q9P2W9, (Mouse) Q8VDS8, (Rat) Q68FW4
Entrez Gene ID: (Human) 53407, (Mouse) 71116, (Rat) 360953
transport
intracellular protein transport
retrograde vesicle-mediated transport, Golgi to ER
protein transport
vesicle-mediated transport
membrane fusion
endoplasmic reticulum membrane organization
positive regulation of organelle assembly
positive regulation of ER to Golgi vesicle-mediated transport
regulation of Golgi organization
ER to Golgi vesicle-mediated transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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