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OriGene
STX3 Monoclonal Antibody (OTI3D6), TrueMAB™
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FIGURE: 1 / 1
STX3 Antibody (CF811074) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY STX3 (RC200658, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-STX3. (1. Positive lysates LY418166 (100 µg) and LC418166 (20 µg) can be purchased separately from OriGene.
Product Details
CF811074
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI3D6
Immunogen
Full length human recombinant protein of human STX3 produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: syntaxin 3A; Syntaxin-3
Gene Aliases: STX3; STX3A; Syn-3
UniProt ID: (Human) Q13277, (Mouse) Q64704, (Rat) Q08849
Entrez Gene ID: (Human) 6809, (Mouse) 20908, (Rat) 81802
transport
neurotransmitter transport
intracellular protein transport
exocytosis
positive regulation of cell proliferation
vesicle-mediated transport
neuron projection development
synaptic vesicle fusion to presynaptic active zone membrane
positive regulation of cell adhesion
vesicle docking
positive regulation of chemotaxis
long-term synaptic potentiation
membrane fusion
positive regulation of protein localization to plasma membrane
positive regulation of protein localization to cell surface
synaptic vesicle docking
intracellular transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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