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Proteintech
STXBP2 Monoclonal Antibody (3G3A12)
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Product Details
66238-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3G3A12
Immunogen
STXBP2 Fusion Protein Ag7640 (241-590 aa encoded by BC002869)
Conjugate
Form
Liquid
Concentration
1.5 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LHELTFQAM AYDLLDIEQD TYRYETTGLS EAREKAVLLD EDDDLWVELR HMHIADVSKK VTELLRTFCE SKRLTTDKAN IKDLSQILKK MPQYQKELNK YSTHLHLADD CMKHFKGSVE KLCSVEQDLA MGSDAEGEKI KDSMKLIVPV LLDAAVPAYD KIRVLLLYIL LRNGVSEENL AKLIQHANVQ AHSSLIRNLE QLGGTVTNPG GSGTSSRLEP RERMEPTYQL SRWTPVIKDV MEDAVEDRLD RNLWPFVSDP APTASSQAAV SARFGHWHKN KAGIEARAGP RLIVYVMGGV AMSEMRAAYE VTRATEGKWE VLIGSSHILT PTRFLDDLKA LDKKLEDIAL P (241-590 aa encoded by BC002869)
Target Information
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Munc18-2; MUSEC1; Protein unc-18 homolog 2; Protein unc-18 homolog B; syntaxin binding protein Munc18-2; Syntaxin-binding protein 2; unc-18 homolog 2; Unc-18B; Unc18-2
Gene Aliases: C79054; FHL5; Hunc18b; Munc-18-2; Munc-18b; MUNC18-2; Munc18b; muSec1; pp10122; STXBP2; Sxtbp2; Sxtp2; UNC18-2; UNC18B
UniProt ID: (Human) Q15833, (Mouse) Q64324
Entrez Gene ID: (Human) 6813, (Mouse) 20911
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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