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Invitrogen
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Positive Samples: U-251MG, HepG2, A-549, Mouse thymus, Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Rat liver
Immunogen sequence: CSYTASRQHL YVDKNTKIIC QGFTGKQGTF HSQQALEYGT KLVGGTTPGK GGQTHLGLPV FNTVKEAKEQ TGATASVIYV PPPFAAAAIN EAIEAEIPLV VCITEGIPQQ DMVRVKHKLL RQEKTRLIGP NCPGVINPGE CKIGIMPGHI HKKGRIGIVS RSGTLTYEAV HQTTQVGLGQ SLCVGIGGDP FNGTDFIDCL EIFLNDSATE GIILIGEIGG NAEENAAEFL KQHNSGPNSK PVVSFIAGLT APPGRRMGHA GAIIAGGKGG AKEKISALQS AGVVVSMSPA QLGTTIYKEF EKRKML
This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: SCS-alpha; Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinate-CoA ligase, alpha subunit; succinate-CoA ligase, GDP-forming alpha subunit; succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial; succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase subunit alpha
Gene Aliases: 1500000I01Rik; GALPHA; MTDPS9; SUCLA1; SUCLG1
UniProt ID: (Human) P53597, (Rat) P13086, (Mouse) Q9WUM5
Entrez Gene ID: (Human) 8802, (Rat) 114597, (Mouse) 56451
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