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Invitrogen
SULT1A1 Recombinant Rabbit Monoclonal Antibody (034)
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FIGURE: 1 / 3
SULT1A1 Antibody (MA5-29590) in ICC/IF
Immunofluorescence staining of SULT1A1 in HepG2 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with SULT1A1 Recombinant Rabbit Monoclonal Antibody (34) (Product # MA5-29590, 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm.
Product Details
MA5-29590
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
034
Immunogen
Recombinant Human SULT1A1 protein (Glu2-Leu295)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2785431
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human SULT1A1.
Target Information
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. Members of the three groups comprising this superfamily (namely SULT1, SULT2 and SULT3) show selectivity to certain substrate compounds. SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein that localizes to the cytoplasm and belongs to the sulfotransferase family. Functioning as a homodimer that is expressed in brain, liver, skin and lung tissue, SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters and, via this catalytic activity, plays a role in the elimination of a variety of compounds from the body. Additionally, SULT1A1 may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aryl sulfotransferase 1; CSPS; HAST1/HAST2; MGC131921; MGC5163; OTTHUMP00000162568; OTTHUMP00000162569; P PST; P PST 1; P-PST 1; Phenol sulfotransferase 1; Phenol-sulfating phenol sulfotransferase 1; ST1A1; ST1A3; Sulfotransferase 1A1; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; Thermostable phenol sulfotransferase; thermostable phenol sulfotransferase1; Ts-PST
Gene Aliases: HAST1/HAST2; OK/SW-cl.88; P-PST; PST; ST1A1; ST1A3; STP; STP1; SULT1A1; TSPST1
UniProt ID: (Human) P50225
Entrez Gene ID: (Human) 6817
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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