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Positive control: Hela cell lysates
Cellular location: Cytoplasmic and Nuclear.
Small ubiquitin-related modifier proteins are members of the ubiquitin-like protein family. SUMO-3 regulates Amyloid beta generation and may be critical in the onset or progression of Alzheimer's disease. SUMO-2/3 forms poly-. SUMO-1, 2, and 3 proteins localize to the nuclear membrane, nuclear bodies, and cytoplasm, respectively. SUMOylation is essential for mammalian cell cycle regulation, SUMO-2/3 localizes to centromeres and condensed chromosomes where binds CENP-E.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Small ubiquitin-related modifier 3; SMT3 homolog 1; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 3; Smt3A; SUMO-2; SUMO-3; Ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B
Gene Aliases: SMT3A; Smt3B; SMT3H1; SUMO-3; SUMO3
UniProt ID: (Human) P55854
Entrez Gene ID: (Human) 6612
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