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Proteintech
SUMO2/3 Polyclonal Antibody
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Product Details
11251-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SUMO2/3 Fusion Protein Ag1778 (1-95 aa encoded by BC016775)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MADEKPKEG VKTENNDHIN LKVAGQDGSV VQFKIKRHTP LSKLMKAYCE RQGLSMRQIR FRFDGQPINE TDTPAQLEME DEDTIDVFQQ QTGGVY (1-95 aa encoded by BC016775)
Target Information
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GMP1; HSMT3; Sentrin; sentrin 2; Sentrin-2; Small ubiquitin-related modifier 2; Small ubiquitin-related modifier 3; SMT3 (supressor of mif two, 3) homolog 1; SMT3 homolog 1; SMT3 homolog 2; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 3; SMT3 supressor of mif two 3 homolog 2; Smt3A; Smt3B; SMT3C; SMT3H3; SUMO-1; SUMO-2; SUMO-3; Ubiquitin-like protein SMT3A; Ubiquitin-like protein SMT3B; UBL1
Gene Aliases: 2810014B19Rik; D10Ertd345e; HSMT3; SMT3A; SMT3B; SMT3H1; SMT3H2; SUMO-2; SUMO-3; SUMO2; SUMO3
UniProt ID: (Human) P61956, (Human) P55854, (Rat) P61959, (Mouse) P61957, (Rat) Q5XIF4, (Mouse) Q9Z172
Entrez Gene ID: (Human) 6613, (Human) 6612, (Rat) 690244, (Mouse) 170930, (Rat) 499417, (Mouse) 20610
protein sumoylation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
cellular protein localization
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
global genome nucleotide-excision repair
protein localization to nucleus
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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