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Invitrogen
SUMO2/SUMO3 Recombinant Rabbit Monoclonal Antibody (JJ087-04)
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FIGURE: 1 / 8
SUMO2/SUMO3 Antibody (MA5-32427) in ICC/IF
Immunocytochemical analysis of SUMO2/SUMO3 in RH-35 cells using a SUMO2/SUMO3 Monoclonal antibody (Product # MA5-32427) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Product Details
MA5-32427
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JJ087-04
Immunogen
Synthetic peptide within Human Sumo 3 aa 11-60
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2809705
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GMP1; HSMT3; Sentrin; sentrin 2; Sentrin-2; Small ubiquitin-related modifier 2; Small ubiquitin-related modifier 3; SMT3 (supressor of mif two, 3) homolog 1; SMT3 homolog 1; SMT3 homolog 2; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 3; SMT3 supressor of mif two 3 homolog 2; Smt3A; Smt3B; SMT3C; SMT3H3; SUMO-1; SUMO-2; SUMO-3; Ubiquitin-like protein SMT3A; Ubiquitin-like protein SMT3B; UBL1
Gene Aliases: 2810014B19Rik; D10Ertd345e; HSMT3; SMT3A; SMT3B; SMT3H1; SMT3H2; SUMO-2; SUMO-3; SUMO2; SUMO3
UniProt ID: (Human) P61956, (Human) P55854, (Rat) P61959, (Mouse) P61957, (Rat) Q5XIF4, (Mouse) Q9Z172
Entrez Gene ID: (Human) 6613, (Human) 6612, (Rat) 690244, (Mouse) 170930, (Rat) 499417, (Mouse) 20610
protein sumoylation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
cellular protein localization
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
global genome nucleotide-excision repair
protein localization to nucleus
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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