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Product Details
PA5-72988
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide made to an internal portion of the human SUV420h1 protein (between residues 100-150) [UniProt Q4FZB7]
Conjugate
Form
Liquid
Concentration
1.14 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 30% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2718842
Target Information
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [histone H4]-lysine20 N-methyltransferase KMT5B; [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B; C630029K18Rik; Histone-lysine N-methyltransferase KMT5B; histone-lysine N-methyltransferase SUV420H1; lysine (K)-specific methyltransferase 5B; Lysine N-methyltransferase 5B; Lysine-specific methyltransferase 5B; MGC118906; MGC118909; MGC21161; MGC703; Su(var)4-20 homolog 1; Suppressor of variegation 4-20 homolog 1; suv4-20h1; SUV420
Gene Aliases: AA117471; C630029K18Rik; CGI-85; CGI85; KMT5B; Suv4-20h1; SUV420H1
UniProt ID: (Human) Q4FZB7, (Mouse) Q3U8K7
Entrez Gene ID: (Human) 51111, (Mouse) 225888
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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