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SYCN Antibody (H00342898-D01P) in WB
Western Blot analysis of SYCN expression in transfected 293T cell line (H00342898-T01) by SYCN MaxPab polyclonal antibody.
Lane 1: SYCN transfected lysate(14.40 KDa).
Lane 2: Non-transfected lysate.
Lane 1: SYCN transfected lysate(14.40 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00342898-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SYCN (NP_001073937.1, 1 a.a. approximately 134 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MSPLRPLLLA LALASVPCAQ GACPASADLK HSDGTRTCAK LYDKSDPYYE NCCGGAELSL ESGADLPYLP SNWANTASSL VVAPRCELTV WSRQGKAGKT HKFSAGTYPR LEEYRRGILG DWSNAISALY CRCS
Target Information
Syncollin is a 134 amino acid, small peripheral membrane protein abundantly expressed in pancreatic acinar cells and is tightly associated with the lumenal side of the zymogen granule membrane. It contains intrachain disulfide bonds. Syncollin is also known to associate with lipid rafts in a cholesterol-dependent manner. In pancreatic acinar cells, syncollin helps in exocytosis and also plays a role in maturation and/or concentration of zymogens in zymogen granules. Reports suggest that syncollin may also have a pore-forming activity on membranes and regulate exocytosis insome exocrine tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ27441; insulin synthesis associated 1; Insulin synthesis-associated protein 1; Syncollin
Gene Aliases: INSSA1; SYCN; SYL
UniProt ID: (Human) Q0VAF6
Entrez Gene ID: (Human) 342898
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