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Invitrogen
SYNGR3 Polyclonal Antibody
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Product Details
PA5-20878
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 19 amino acid peptide from near the carboxy terminus of human SYNGR3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11152217
Product Specific Information
A suggested positive control is mouse brain tissue lysate.
PA5-20878 can be used with blocking peptide PEP-0992.
Target Information
Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. SYNGR3 is predominantly expressed in brain and placenta. SYNGR3 is involved in the positive regulation of dopamine transporter activity and facilitates the physical and functional interactions of the transporter with the dopamine vesicular storage system, allowing a more efficient loading of the vesicles with extracellular dopamine after release.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sgyr III; synaptogryin III; Synaptogyrin-3
Gene Aliases: SYNGR3
UniProt ID: (Human) O43761, (Mouse) Q8R191
Entrez Gene ID: (Human) 9143, (Mouse) 20974, (Rat) 302975
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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