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Proteintech
SYNJ2BP Polyclonal Antibody
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Product Details
15666-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SYNJ2BP Fusion Protein Ag8130 (1-112 aa encoded by BC007704)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MNGRVDYLV TEEEINLTRG PSGLGFNIVG GTDQQYVSND SGIYVSRIKE NGAAALDGRL QEGDKILSVN GQDLKNLLHQ DAVDLFRNAG YAVSLRVQHR LQVQNGPIGH RGE (1-112 aa encoded by BC007704)
Target Information
Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: activin receptor interacting protein 2; activin receptor interacting protein 5; Activin receptor-interacting protein 2; activin receptor-interacting protein 2a; Activin receptor-interacting protein 4; Mitochondrial outer membrane protein 25; NPW16; outer membrane protein; outer membrane protein 25; Synaptojanin-2-binding protein; synj2bp
Gene Aliases: AA409442; ActRIP4; ARIP2; ARIP2a; D12Wsu118e; OMP25; SYNJ2BP
UniProt ID: (Human) P57105, (Rat) Q9WVJ4, (Mouse) Q9D6K5
Entrez Gene ID: (Human) 55333, (Rat) 64531, (Mouse) 24071
positive regulation of receptor internalization
protein targeting
Rho protein signal transduction
regulation of endocytosis
negative regulation of activin receptor signaling pathway
positive regulation of activin receptor signaling pathway
intracellular distribution of mitochondria
positive regulation of protein localization to cell surface
cytoplasm organization
negative regulation of endothelial cell proliferation
regulation of Notch signaling pathway
negative regulation of endothelial cell migration
negative regulation of angiogenesis
negative regulation of ERK1 and ERK2 cascade
negative regulation of sprouting angiogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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