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Invitrogen
SYNJ2BP Polyclonal Antibody
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Product Details
PA5-51471
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SYNJ2BP. Recombinant protein control fragment (Product #RP-88909).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2648143
Product Specific Information
Immunogen sequence: NGRVDYLVTE EEINLTRGPS GLGFNIVGGT DQQYVSNDSG IYVSRIKENG AAALDGRLQE GDKILSVNGQ DLKNLLHQDA VDLFRNAGYA VSLRVQHRLQ VQNGPIGHRG EG
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
Target Information
Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: activin receptor interacting protein 2; activin receptor interacting protein 5; Activin receptor-interacting protein 2; activin receptor-interacting protein 2a; Activin receptor-interacting protein 4; Mitochondrial outer membrane protein 25; outer membrane protein 25; Synaptojanin-2-binding protein; synj2bp
Gene Aliases: AA409442; ActRIP4; ARIP2; ARIP2a; D12Wsu118e; OMP25; SYNJ2BP
UniProt ID: (Human) P57105, (Mouse) Q9D6K5
Entrez Gene ID: (Human) 55333, (Mouse) 24071
protein targeting
cytoplasm organization
Rho protein signal transduction
regulation of endocytosis
intracellular distribution of mitochondria
negative regulation of endothelial cell proliferation
positive regulation of receptor internalization
regulation of Notch signaling pathway
negative regulation of endothelial cell migration
negative regulation of angiogenesis
negative regulation of activin receptor signaling pathway
positive regulation of activin receptor signaling pathway
negative regulation of ERK1 and ERK2 cascade
negative regulation of sprouting angiogenesis
positive regulation of protein localization to cell surface
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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