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Invitrogen
SYT10 Polyclonal Antibody
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SYT10 Antibody (PA5-104173) in IHC (P)
Immunohistochemistry analysis of SYT10 in mouse muscle tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with SYT10 polyclonal antibody (Product # PA5-104173) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-104173
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SYT10(Accession Q6XYQ8), corresponding to amino acid residues R417-C467.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2853501
Product Specific Information
Antibody detects endogenous levels of total SYT10.
Target Information
SYT10 is a Ca2+ sensor specifically required for the Ca2+-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. SYT10 is not involved in Ca2+-dependent synaptic vesicle exocytosis. It acts through Ca2+ and phospholipid binding to the C2 domain: Ca2+ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp781D2042; P65; SVP65; synaptotagmin 10; Synaptotagmin X; Synaptotagmin-10; SYT; SYT-10; SytX
Gene Aliases: SYT10
UniProt ID: (Human) Q6XYQ8, (Mouse) Q9R0N4, (Rat) O08625
Entrez Gene ID: (Human) 341359, (Mouse) 54526, (Rat) 60567
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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