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Invitrogen
SYT11 Recombinant Rabbit Monoclonal Antibody (2M4R9)
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FIGURE: 1 / 1
SYT11 Antibody (MA5-55562) in WB
Western Blot analysis of various lysates using SYT11 Recombinant Monoclonal Antibody (Product # MA5-55562) at 1:2,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
MA5-55562
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
2M4R9
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 37-200 of human Synaptotagmin XI (SYT11).
Conjugate
Form
Liquid
Concentration
1.31 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
RRID
AB_3667801
Product Specific Information
Immunogen Sequence: WSCCHQQAEK KQKNPPYKFI HMLKGISIYP ETLSNKKKII KVRRDKDGPG REGGRRNLLV DAAEAGLLSR DKDPRGPSSG SCIDQLPIKM DYGEELRSPI TSLTPGESKT TSPSSPEEDV MLGSLTFSVD YNFPKKALVV TIQEAHGLPV MDDQTQGSDP YIKM
Target Information
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: synaptotagmin 11; synaptotagmin 12; Synaptotagmin XI; Synaptotagmin-11; SytXI
Gene Aliases: 1500004A13Rik; 3632445O20Rik; 5430404N14Rik; 6530420C11Rik; AI851970; KIAA0080; SYT11; SYT12; sytXI
UniProt ID: (Human) Q9BT88, (Mouse) Q9R0N3, (Rat) O08835
Entrez Gene ID: (Human) 23208, (Mouse) 229521, (Rat) 60568
synaptic vesicle exocytosis
regulation of calcium ion-dependent exocytosis
calcium ion-regulated exocytosis of neurotransmitter
plasma membrane repair
vesicle fusion
negative regulation of neurotransmitter secretion
protein homotetramerization
negative regulation of interleukin-6 secretion
negative regulation of tumor necrosis factor secretion
regulation of phagosome maturation
positive regulation of protein localization to phagocytic vesicle
calcium ion regulated lysosome exocytosis
transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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