Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
OriGene
SYT11 Monoclonal Antibody (OTI3F3), TrueMAB™
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 1
SYT11 Antibody (TA810985) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SYT11 (RC205445, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SYT11. Positive lysates LY407700 (100 µg) and LC407700 (20 µg) can be purchased separately from OriGene.
Product Details
TA810985
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI3F3
Immunogen
Human recombinant protein fragment corresponding to amino acids 42-296 of human SYT11 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: synaptotagmin 12; Synaptotagmin XI; Synaptotagmin-11; SytXI
Gene Aliases: KIAA0080; SYT11; SYT12; sytXI
UniProt ID: (Human) Q9BT88
Entrez Gene ID: (Human) 23208
plasma membrane repair
vesicle fusion
regulation of calcium ion-dependent exocytosis
negative regulation of neurotransmitter secretion
calcium ion-regulated exocytosis of neurotransmitter
protein homotetramerization
negative regulation of interleukin-6 secretion
negative regulation of tumor necrosis factor secretion
regulation of phagosome maturation
positive regulation of protein localization to phagocytic vesicle
calcium ion regulated lysosome exocytosis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support