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Invitrogen
SYTL2 Polyclonal Antibody
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SYTL2 Antibody (PA5-24730) in IHC (P)
Immunohistochemistry analysis of SYTL2 in formalin fixed and paraffin embedded brain tissue. Samples were incubated with SYTL2 polyclonal antibody (Product # PA5-24730) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-24730
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 840-868 amino acids from the central region of human SYTL2
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2542230
Target Information
SYTL2 is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Breast cancer-associated antigen SGA-72M; chromosome 11 synaptotagmin; Exophilin-4; protein phosphatase 1, regulatory subunit 151; synaptotagmin-like 2; Synaptotagmin-like protein 2
Gene Aliases: CHR11SYT; EXO4; KIAA1597; PPP1R151; SGA72M; SLP2; SLP2A; SYTL2
UniProt ID: (Human) Q9HCH5
Entrez Gene ID: (Human) 54843
intracellular protein transport
exocytosis
vesicle docking involved in exocytosis
vesicle fusion
negative regulation of phosphatase activity
vesicle-mediated transport
regulation of calcium ion-dependent exocytosis
calcium ion-regulated exocytosis of neurotransmitter
positive regulation of mucus secretion
protein localization to plasma membrane
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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