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SYTL4 Antibody (PA5-35992) in IHC (P)
SYTL4 Polyclonal Antibody detects SYTL4 protein at cytosol on mouse pancreas by immunohistochemical analysis. Sample: Paraffin-embedded mouse pancreas. SYTL4 Polyclonal Antibody (Product # PA5-35992) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-35992
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human SYTL4. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2553302
Product Specific Information
Recommended positive controls: 293T, A431, HeLa.
Predicted reactivity: Mouse (86%), Rat (89%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Exophilin-2; Granuphilin; granuphilin-a; granuphilin-b; Synaptotagmin-like protein 4
Gene Aliases: Gph; SLP4; SYTL4
UniProt ID: (Human) Q96C24, (Mouse) Q9R0Q1
Entrez Gene ID: (Human) 94121, (Mouse) 27359
intracellular protein transport
exocytosis
synaptic vesicle exocytosis
regulation of calcium ion-dependent exocytosis
positive regulation of exocytosis
negative regulation of insulin secretion
calcium ion-regulated exocytosis of neurotransmitter
positive regulation of protein secretion
multivesicular body sorting pathway
vesicle fusion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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