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Immunogen sequence: RLKNELLEIK RKGAKRGSQH YSDRTCARCQ ESLGRLSPKT NTCRGCNHLV CRDCRIQESN GTWRCKVCAK EIELKKATGD WFYDQKVNRF AYRTGSEIIR MSLRHKPAVS KRETVGQSLL HQTQMGDIWP GRKIIQERQK EPSVLFEVP
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 89%.
This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exophilin-2; Granuphilin; granuphilin-a; Synaptotagmin-like protein 4
Gene Aliases: SLP4; SYTL4
UniProt ID: (Human) Q96C24
Entrez Gene ID: (Human) 94121
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