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SYTL4 Antibody (CF810588) in IHC (P)
Immunohistochemical staining of paraffin-embedded human prostate tissue within the normal limits using anti-SYTL4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA810588)(1:500).
Product Details
CF810588
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI3C8
Immunogen
Full length human recombinant protein of human SYTL4 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Exophilin-2; Granuphilin; granuphilin b; granuphilin-a; granuphilin-b; synaptotagmin-like 4 (granuphilin-a); Synaptotagmin-like protein 4
Gene Aliases: Gph; SLP4; SYTL4
UniProt ID: (Human) Q96C24, (Mouse) Q9R0Q1, (Rat) Q8VHQ7
Entrez Gene ID: (Human) 94121, (Mouse) 27359, (Rat) 140594
intracellular protein transport
exocytosis
synaptic vesicle exocytosis
regulation of calcium ion-dependent exocytosis
positive regulation of exocytosis
negative regulation of insulin secretion
calcium ion-regulated exocytosis of neurotransmitter
positive regulation of protein secretion
multivesicular body sorting pathway
vesicle fusion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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