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Product Details
PA5-21176
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 17 amino acid peptide near the amino terminus of human SYTL5.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11157463
Product Specific Information
A suggested positive control is Hela cell lysate.
PA5-21176 can be used with blocking peptide PEP-1290.
Target Information
SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: exophilin 9; synaptotagmin 15; synaptotagmin-like 5; Synaptotagmin-like protein 5
Gene Aliases: ENSMUSG00000054453; SLP5; SYTL5
UniProt ID: (Human) Q8TDW5, (Mouse) Q80T23, (Rat) Q812E4
Entrez Gene ID: (Human) 94122, (Mouse) 236643, (Rat) 302538
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