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Invitrogen
SYTL5 Polyclonal Antibody
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Product Details
PA5-55284
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SYTL5. Recombinant protein control fragment (Product #RP-91897).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2648170
Product Specific Information
Immunogen sequence: KQVNVLGTDV VRQSILRRSP AEEVQSQEQT RQDAEKSDTS PVAGKKASHD GPKRKGFLLS KFRSATRGEI ITPKTDTGRS YSLDLDGQHF RSLKSPPGSD RGSTGSSDLN DQEP
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 75%.
Target Information
SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: exophilin 9; synaptotagmin-like 5; Synaptotagmin-like protein 5
Gene Aliases: SLP5; SYTL5
UniProt ID: (Human) Q8TDW5
Entrez Gene ID: (Human) 94122
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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