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This target displays homology in the following species: Cow: 83%; Dog: 92%; Guinea Pig: 93%; Horse: 83%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 92%
Sarcalumenin is a 160 kDa acidic calcium binding glycoprotein found to reside at the inner membrane of the sarcoplasmic reticulum in a calcium dependent manner. The gene encoding sarcalumenin also encodes an alternate splice variant, a 53 kDa glycoprotein which co-localizes with sarcalumenin. These two proteins are found in the longitudinal sarcoplasmic reticulum and the nonjunctional membranes of the terminal cisternae. They have been observed to co-localize with calcium-ATPase suggesting that they are involved in calcium transport and sequestration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Sarcalumenin
Gene Aliases: SRL
UniProt ID: (Human) Q86TD4
Entrez Gene ID: (Human) 6345
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