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Proteintech
Secretogranin V Polyclonal Antibody
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Product Details
10761-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Secretogranin V Fusion Protein Ag1107 (1-212 aa encoded by BC005349)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MVSRMVSTM LSGLLFWLAS GWTPAFAYSP RTPDRVSEAD IQRLLHGVME QLGIARPRVE YPAHQAMNLV GPQSIEGGAH EGLQHLGPFG NIPNIVAELT GDNIPKDFSE DQGYPDPPNP CPVGKTADDG CLENTPDTAE FSREFQLHQH LSDPEHDYPG LGKWNKKLLY EKMKGGERRK RRSVNPYLQG QRLDNVVAKK SVPHFSDEDK DPE (1-212 aa encoded by BC005349)
Target Information
Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Neuroendocrine protein 7B2; P SGNE1; Pituitary polypeptide; prohormone convertase chaperone; Secretogranin V; secretogranin V (7B2 protein); Secretogranin-5; Secretory granule endocrine protein I; secretory granule neuroendocrine protein 1; secretory granule neuroendocrine protein 1, 7B2 protein; Secretory granule neuroendocrine, protein 1 (7B2 protein); secretory granule, neuroendocrine protein 1 (7B2 protein)
Gene Aliases: 7B2; AI325031; P7B2; SCG5; Sgne-1; SGNE1; SgV
UniProt ID: (Human) P05408, (Mouse) P12961, (Rat) P27682
Entrez Gene ID: (Human) 6447, (Mouse) 20394, (Rat) 25719
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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