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Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: MAYFDPDFYA SAPGHKHVPD WV
The multi-pass transmembrane protein encoded by this gene belongs to the CDP-alcohol phosphatidyltransferase class-I family. It catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine, which is involved in the formation and maintenance of vesicular membranes, regulation of lipid metabolism, and protein folding. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. A pseudogene of this locus has been identified on chromosome 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ethanolaminephosphotransferase 1; hEPT1; Selenoprotein I; SelI
Gene Aliases: EPT1; KIAA1724; SELENOI; SELI; SEPI
UniProt ID: (Human) Q9C0D9
Entrez Gene ID: (Human) 85465
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