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Proteintech
Sestrin 2 Monoclonal Antibody (1A1A4), CoraLite® 594
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Product Details
CL59466297100UL
Product Specifications
Species Reactivity
Human,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1A1A4
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hypoxia induced gene 95; hypoxia-induced; Hypoxia-induced gene; Sestrin-2
Gene Aliases: HI95; RGD1566319; SES2; SESN2; SEST2
UniProt ID: (Human) P58004
Entrez Gene ID: (Human) 83667, (Rat) 502988
regulation of protein phosphorylation
fatty acid beta-oxidation
autophagy
mitochondrion organization
response to glucose
mitochondrial DNA metabolic process
response to insulin
glucose homeostasis
protein kinase B signaling
glucose import
triglyceride homeostasis
regulation of gluconeogenesis involved in cellular glucose homeostasis
regulation of response to reactive oxygen species
regulation of cAMP-dependent protein kinase activity
positive regulation of macroautophagy
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
cellular response to oxidative stress
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
cellular response to amino acid stimulus
cellular response to leucine
reactive oxygen species metabolic process
cellular oxidant detoxification
positive regulation of protein localization to nucleus
negative regulation of translation in response to endoplasmic reticulum stress
negative regulation of TORC1 signaling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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