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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Sigma-1 Receptor Antibodies

          Invitrogen

          Sigma-1 Receptor Recombinant Rabbit Monoclonal Antibody (HL2230)

          View all (11) Sigma-1 Receptor antibodies
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          Datasheet
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          Cite Sigma-1 Receptor Recombinant Rabbit Monoclonal Antibody (HL2230)

          • Antibody Testing Data (5)
          Sigma-1 Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Sigma-1 Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          Sigma-1 Receptor Antibody (MA5-50446) in IHC (P)

          Immunohistochemical analysis of Sigma-1 Receptor using Sigma-1 Receptor Recombinant Monoclonal Antibody (Product # MA5-50446) in Paraffin embedded mouse brain tissue at a dilution of 1:100. For Antigen retrieval citrate buffer, pH 6.0, as used for 15 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Sigma-1 Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Sigma-1 Receptor Antibody in Western Blot (WB)
          Sigma-1 Receptor Antibody in Western Blot (WB)
          Sigma-1 Receptor Antibody in Western Blot (WB)
          Sigma-1 Receptor Antibody in Western Blot (WB)

          Product Details

          MA5-50446

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          Assay-dependent
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293 cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          HL2230

          Immunogen

          Recombinant fragment of human SIGMAR1.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3094287

          Target Information

          This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Aging-associated gene 8 protein; AL024364; mSigmaR1; opioid receptor, sigma 1; RP23 167I12.6; SIG 1R; SIG-1R; sigma 1 receptor variant SR-1D; Sigma 1-type opioid receptor; Sigma non-opioid intracellular receptor 1; Sigma-1 Receptor; sigma1 receptor; Sigma1-receptor; sigma1R; SR BP; SR-BP; SR31747 binding protein 1; SR31747-binding protein

          View more View less

          Gene Aliases: AAG8; ALS16; DSMA2; hSigmaR1; OPRS1; SIG-1R; sigma1R; SIGMAR1; SR-BP; SR-BP1; SRBP

          View more View less

          UniProt ID: (Human) Q99720, (Rat) Q9R0C9, (Mouse) O55242

          View more View less

          Entrez Gene ID: (Human) 10280, (Rat) 29336, (Mouse) 18391

          View more View less

          Function(s)
          opioid receptor activity drug binding receptor activity protein binding
          Process(es)
          lipid transport nervous system development opioid receptor signaling pathway regulation of neuron apoptotic process protein homotrimerization transport
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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