Product References
Association between radioactive iodine uptake and neutropenia in untreated Graves' disease.
Endocrine connections
Yang Q,Ke W,Pan F,Huang X,Liu J,Zha B
Wed Feb 01 00:00:00 UTC 2023
TESC promotes differentiated thyroid cancer development by activating ERK and weakening NIS and radioiodine uptake.
Endocrine
Guo Y,Cai Y,Song F,Zhu L,Hu Y,Liu Y,Ma W,Ge J,Zeng Q,Ding L,Li L,Zheng G,Ge M
Fri Sep 01 00:00:00 UTC 2023
Iodide Excess Inhibits Thyroid Hormone Synthesis Pathway Involving XBP1-Mediated Regulation.
Nutrients
Yu J,Shen S,Yan Y,Liu L,Luo R,Liu S,Wu Y,Li Y,Jiang J,Ying H
Thu Feb 09 00:00:00 UTC 2023
Iodide Excess Inhibits Thyroid Hormone Synthesis Pathway Involving XBP1-Mediated Regulation.
Nutrients
Yu J,Shen S,Yan Y,Liu L,Luo R,Liu S,Wu Y,Li Y,Jiang J,Ying H
Thu Feb 09 00:00:00 UTC 2023
Lipid-Peptide-mRNA Nanoparticles Augment Radioiodine Uptake in Anaplastic Thyroid Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Li Q,Zhang L,Lang J,Tan Z,Feng Q,Zhu F,Liu G,Ying Z,Yu X,Feng H,Yi H,Wen Q,Jin T,Cheng K,Zhao X,Ge M
Sun Jan 01 00:00:00 UTC 2023
Lipid-Peptide-mRNA Nanoparticles Augment Radioiodine Uptake in Anaplastic Thyroid Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Li Q,Zhang L,Lang J,Tan Z,Feng Q,Zhu F,Liu G,Ying Z,Yu X,Feng H,Yi H,Wen Q,Jin T,Cheng K,Zhao X,Ge M
Sun Jan 01 00:00:00 UTC 2023
Lipid-Peptide-mRNA Nanoparticles Augment Radioiodine Uptake in Anaplastic Thyroid Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Li Q,Zhang L,Lang J,Tan Z,Feng Q,Zhu F,Liu G,Ying Z,Yu X,Feng H,Yi H,Wen Q,Jin T,Cheng K,Zhao X,Ge M
Sun Jan 01 00:00:00 UTC 2023
Generation of a NIS-EGFP-Fluc triple-reporter human embryonic stem cell line by PiggyBac transposon system.
Stem cell research
Huang P,Tian C,Chen Y,Zhou M,Ni J,Niu M,Liu X,Peng Z
Thu Dec 01 00:00:00 UTC 2022
High concentration of estradiol has a negative correlation with free thyroxine during the second trimester of pregnancy.
Endocrine connections
He L,Li X,Chen Z,Wang W,Wang K,Huang X,Yang Q,Ke W,Liu J,Zha B
Sat Oct 01 00:00:00 UTC 2022
Di(2-ethylhexyl) phthalate induced thyroid toxicity via endoplasmic reticulum stress: In vivo and in vitro study.
Environmental toxicology
Xu Q,Zhao T,Ri H,Ye J,Zhao W,Zhang Y,Ye L
Thu Dec 01 00:00:00 UTC 2022
IGF2BP2-dependent activation of ERBB2 signaling contributes to acquired resistance to tyrosine kinase inhibitor in differentiation therapy of radioiodine-refractory papillary thyroid cancer.
Cancer letters
Sa R,Liang R,Qiu X,He Z,Liu Z,Chen L
Mon Feb 28 00:00:00 UTC 2022
Targeting IGF2BP2 Promotes Differentiation of Radioiodine Refractory Papillary Thyroid Cancer via Destabilizing RUNX2 mRNA.
Cancers
Sa R,Liang R,Qiu X,He Z,Liu Z,Chen L
Tue Mar 01 00:00:00 UTC 2022
Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter.
Cell chemical biology
Read ML,Brookes K,Thornton CEM,Fletcher A,Nieto HR,Alshahrani M,Khan R,Borges de Souza P,Zha L,Webster JRM,Alderwick LJ,Campbell MJ,Boelaert K,Smith VE,McCabe CJ
Thu Mar 17 00:00:00 UTC 2022
Adherens Junction Integrity Is a Critical Determinant of Sodium Iodide Symporter Residency at the Plasma Membrane of Thyroid Cells.
Cancers
Faria M,Vareda J,Miranda M,Bugalho MJ,Silva AL,Matos P
Mon Oct 31 00:00:00 UTC 2022
Mechanisms of Sodium/Iodide Symporter-Mediated Mammary Gland Iodine Compensation during Lactation.
Nutrients
Fu M,Gao Y,Guo W,Meng Q,Jin Q,Yang R,Yang Y,Zhang Y,Zhang W
Wed Aug 31 00:00:00 UTC 2022
Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.
Environmental toxicology and pharmacology
Xu Q,Zhou L,Ri H,Li X,Zhang X,Qi W,Ye L
Tue Nov 01 00:00:00 UTC 2022
Analysis of NIS Plasma Membrane Interactors Discloses Key Regulation by a SRC/RAC1/PAK1/PIP5K/EZRIN Pathway with Potential Implications for Radioiodine Re-Sensitization Therapy in Thyroid Cancer.
Cancers
Faria M,Domingues R,Bugalho MJ,Silva AL,Matos P
Sat Oct 30 00:00:00 UTC 2021
Analysis of NIS Plasma Membrane Interactors Discloses Key Regulation by a SRC/RAC1/PAK1/PIP5K/EZRIN Pathway with Potential Implications for Radioiodine Re-Sensitization Therapy in Thyroid Cancer.
Cancers
Faria M,Domingues R,Bugalho MJ,Silva AL,Matos P
Sat Oct 30 00:00:00 UTC 2021
Analysis of NIS Plasma Membrane Interactors Discloses Key Regulation by a SRC/RAC1/PAK1/PIP5K/EZRIN Pathway with Potential Implications for Radioiodine Re-Sensitization Therapy in Thyroid Cancer.
Cancers
Faria M,Domingues R,Bugalho MJ,Silva AL,Matos P
Sat Oct 30 00:00:00 UTC 2021
Downregulation of Rap1GAP Expression Activates the TGF-β/Smad3 Pathway to Inhibit the Expression of Sodium/Iodine Transporter in Papillary Thyroid Carcinoma Cells.
BioMed research international
Yan Z,Yangyanqiu W,Shuwen H,Jing M,Haihong L,Gong C,Yin J,Qing Z,Weili G
Tue Jan 18 00:00:00 UTC 2022
MAPK Inhibition Requires Active RAC1 Signaling to Effectively Improve Iodide Uptake by Thyroid Follicular Cells.
Cancers
Faria M,Domingues R,Bugalho MJ,Matos P,Silva AL
Mon Nov 22 00:00:00 UTC 2021
Proteomics and Organoid Culture Reveal the Underlying Pathogenesis of Hashimoto's Thyroiditis.
Frontiers in immunology
Xiao H,Liang J,Liu S,Zhang Q,Xie F,Kong X,Guo S,Wang R,Fu R,Ye Z,Li Y,Zhang S,Zhang L,Kaudimba KK,Wang R,Kong X,Zhao B,Zheng X,Liu T
Mon Feb 14 00:00:00 UTC 2022
PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism.
The Science of the total environment
Ha M,Huang X,Li L,Lu D,Liu C
Thu Feb 25 00:00:00 UTC 2021
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
OncoTargets and therapy
Yang W,Xu X,Xu M,Zhou J,Xi Z,Guo H,Ming J,Huang T
Fri Apr 22 00:00:00 UTC 2022
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Cell death and differentiation
Liao Y,Hua Y,Li Y,Zhang C,Yu W,Guo P,Zou K,Li W,Sun Y,Wang R,Zuo Y,Sui S,Tian C,Hao J,Chen M,Hu S,Chen M,Long Q,Wang X,Zou L,Xie F,Guo W,Deng W
Thu Apr 01 00:00:00 UTC 2021
TNFα-mediated activation of NF-κB downregulates sodium-iodide symporter expression in thyroid cells.
PloS one
Faria M,Domingues R,Paixão F,Bugalho MJ,Matos P,Silva AL
Mon May 04 00:00:00 UTC 2020
Combined tazemetostat and MAPKi enhances differentiation of papillary thyroid cancer cells harbouring BRAFV600E by synergistically decreasing global trimethylation of H3K27.
Journal of cellular and molecular medicine
Fu H,Cheng L,Sa R,Jin Y,Chen L
Sun Mar 01 00:00:00 UTC 2020
Human Bone Marrow Mesenchymal Stem Cells Modified Hybrid Baculovirus-Adeno-Associated Viral Vectors Targeting 131I Therapy of Hypopharyngeal Carcinoma.
Human gene therapy
Wang J,Kong D,Zhu L,Wang S,Sun X
Tue Dec 01 00:00:00 UTC 2020
REGγ ablation impedes dedifferentiation of anaplastic thyroid carcinoma and accentuates radio-therapeutic response by regulating the Smad7-TGF-β pathway.
Cell death and differentiation
Jiao C,Li L,Zhang P,Zhang L,Li K,Fang R,Yuan L,Shi K,Pan L,Guo Q,Gao X,Chen G,Xu S,Wang Q,Zuo D,Wu W,Qiao S,Wang X,Moses R,Xiao J,Li L,Dang Y,Li X
Sat Feb 01 00:00:00 UTC 2020
Patient-Derived Papillary Thyroid Cancer Organoids for Radioactive Iodine Refractory Screening.
Cancers
Sondorp LHJ,Ogundipe VML,Groen AH,Kelder W,Kemper A,Links TP,Coppes RP,Kruijff S
Sat Oct 31 00:00:00 UTC 2020
Human Bone Marrow Mesenchymal Stem Cells Functionalized by Hybrid Baculovirus-Adeno-Associated Viral Vectors for Targeting Hypopharyngeal Carcinoma.
Stem cells and development
Wang J,Zhu L,Chen X,Huang R,Wang S,Dong P
Mon Apr 15 00:00:00 UTC 2019
Dimerization of the Sodium/Iodide Symporter.
Thyroid : official journal of the American Thyroid Association
Thompson RJ,Fletcher A,Brookes K,Nieto H,Alshahrani MM,Mueller JW,Fine NHF,Hodson DJ,Boelaert K,Read ML,Smith VE,McCabe CJ
Tue Oct 01 00:00:00 UTC 2019
A somatic mutation of RasGRP3 decreases Na+/I- symporter expression in metastases of radioactive iodine-refractory thyroid cancer by stimulating the Akt signaling pathway.
American journal of cancer research
Song J,Qiu W,Deng X,Qiu Z,Fan Y,Yang Z
Wed Sep 30 00:00:00 UTC 2020
A somatic mutation of RasGRP3 decreases Na+/I- symporter expression in metastases of radioactive iodine-refractory thyroid cancer by stimulating the Akt signaling pathway.
American journal of cancer research
Song J,Qiu W,Deng X,Qiu Z,Fan Y,Yang Z
Wed Sep 30 00:00:00 UTC 2020
Synergistic inhibition of MEK/ERK and BRAF V600E with PD98059 and PLX4032 induces sodium/iodide symporter (NIS) expression and radioiodine uptake in BRAF mutated papillary thyroid cancer cells.
Thyroid research
Zhang H,Chen D
Mon Mar 21 00:00:00 UTC 2022
Synergistic inhibition of MEK/ERK and BRAF V600E with PD98059 and PLX4032 induces sodium/iodide symporter (NIS) expression and radioiodine uptake in BRAF mutated papillary thyroid cancer cells.
Thyroid research
Zhang H,Chen D
Mon Mar 21 00:00:00 UTC 2022
HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAFV600E.
Oncotarget
Cheng L,Jin Y,Liu M,Ruan M,Chen L
Tue Mar 21 00:00:00 UTC 2017
HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAFV600E.
Oncotarget
Cheng L,Jin Y,Liu M,Ruan M,Chen L
Tue Mar 21 00:00:00 UTC 2017
HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAFV600E.
Oncotarget
Cheng L,Jin Y,Liu M,Ruan M,Chen L
Tue Mar 21 00:00:00 UTC 2017
HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAFV600E.
Oncotarget
Cheng L,Jin Y,Liu M,Ruan M,Chen L
Tue Mar 21 00:00:00 UTC 2017
Use of rhenium-188 for in vivo imaging and treatment of human cervical cancer cells transfected with lentivirus expressing sodium iodide symporter.
Oncology reports
Zhang M,Shi S,Guo R,Miao Y,Li B
Sat Oct 01 00:00:00 UTC 2016
Use of rhenium-188 for in vivo imaging and treatment of human cervical cancer cells transfected with lentivirus expressing sodium iodide symporter.
Oncology reports
Zhang M,Shi S,Guo R,Miao Y,Li B
Sat Oct 01 00:00:00 UTC 2016
2,3',4,4',5-Pentachlorobiphenyl Induces Inflammatory Responses in the Thyroid Through JNK and Aryl Hydrocarbon Receptor-Mediated Pathway.
Toxicological sciences : an official journal of the Society of Toxicology
Xu B,Yang H,Sun M,Chen H,Jiang L,Zheng X,Ding G,Liu Y,Sheng Y,Cui D,Duan Y
Mon Feb 01 00:00:00 UTC 2016
2,3',4,4',5-Pentachlorobiphenyl Induces Inflammatory Responses in the Thyroid Through JNK and Aryl Hydrocarbon Receptor-Mediated Pathway.
Toxicological sciences : an official journal of the Society of Toxicology
Xu B,Yang H,Sun M,Chen H,Jiang L,Zheng X,Ding G,Liu Y,Sheng Y,Cui D,Duan Y
Mon Feb 01 00:00:00 UTC 2016
Iodide- and glucose-handling gene expression regulated by sorafenib or cabozantinib in papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism
Ruan M,Liu M,Dong Q,Chen L
Fri May 01 00:00:00 UTC 2015
Iodide- and glucose-handling gene expression regulated by sorafenib or cabozantinib in papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism
Ruan M,Liu M,Dong Q,Chen L
Fri May 01 00:00:00 UTC 2015
Iodide- and glucose-handling gene expression regulated by sorafenib or cabozantinib in papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism
Ruan M,Liu M,Dong Q,Chen L
Fri May 01 00:00:00 UTC 2015
Iodide- and glucose-handling gene expression regulated by sorafenib or cabozantinib in papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism
Ruan M,Liu M,Dong Q,Chen L
Fri May 01 00:00:00 UTC 2015
Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study.
Frontiers in neuroscience
Saunders NR,Dziegielewska KM,Møllgård K,Habgood MD,Wakefield MJ,Lindsay H,Stratzielle N,Ghersi-Egea JF,Liddelow SA
Thu May 14 00:00:00 UTC 2015
In vivo molecular imaging and radionuclide (131I) therapy of human nasopharyngeal carcinoma cells transfected with a lentivirus expressing sodium iodide symporter.
PloS one
Shi S,Zhang M,Guo R,Miao Y,Hu J,Xi Y,Li B
Mon Jan 04 00:00:00 UTC 2016
In vivo molecular imaging and radionuclide (131I) therapy of human nasopharyngeal carcinoma cells transfected with a lentivirus expressing sodium iodide symporter.
PloS one
Shi S,Zhang M,Guo R,Miao Y,Hu J,Xi Y,Li B
Mon Jan 04 00:00:00 UTC 2016
In vivo molecular imaging and radionuclide (131I) therapy of human nasopharyngeal carcinoma cells transfected with a lentivirus expressing sodium iodide symporter.
PloS one
Shi S,Zhang M,Guo R,Miao Y,Hu J,Xi Y,Li B
Mon Jan 04 00:00:00 UTC 2016
In vivo molecular imaging and radionuclide (131I) therapy of human nasopharyngeal carcinoma cells transfected with a lentivirus expressing sodium iodide symporter.
PloS one
Shi S,Zhang M,Guo R,Miao Y,Hu J,Xi Y,Li B
Mon Jan 04 00:00:00 UTC 2016
Feasibility of lentiviral‑mediated sodium iodide symporter gene delivery for the efficient monitoring of bone marrow‑derived mesenchymal stem cell transplantation and survival.
International journal of molecular medicine
Shi S,Zhang M,Guo R,Miao Y,Zhang M,Hu J,Xi Y,Li B
Mon Dec 01 00:00:00 UTC 2014
