Invitrogen

Sodium Potassium ATPase Recombinant Rabbit Monoclonal Antibody (ST0533)

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View all (2) Sodium Potassium ATPase antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

MA5-32184

Applications
Tested Dilution
Publications

Western Blot (WB)

1:50,000-1:100,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:5,000
-

Immunocytochemistry (ICC/IF)

1:500
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Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ST0533

Immunogen

Synthetic peptide within Human ATP1A1 aa 39-83
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2809472

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: ATPase, Na+/K+ transporting, alpha 1 polypeptide; ATPase, Na+/K+ transporting, alpha 4 polypeptide; ATPase, Na+/K+ transporting, alpha polypeptide-like 2; ATPase, Na+K+ transporting, alpha 1; Na(+)/K(+) ATPase alpha-1 subunit; Na(+)/K(+) ATPase alpha-4 subunit; Na+/K+ ATPase 1; Na+/K+ ATPase 4; Na+/K+ ATPase alpha 4 subunit; Na+/K+ ATPase, alpha-D polypeptide; Na, K-ATPase, alpha-A catalytic polypeptide; Na,K-ATPase alpha-1 subunit; Na,K-ATPase catalytic subunit alpha-A protein; Na,K-ATPase subunit alpha-C; sodium pump 4; Sodium pump subunit alpha-1; Sodium pump subunit alpha-4; sodium-potassium ATPase catalytic subunit alpha-1; sodium-potassium ATPase catalytic subunit alpha-4; sodium-potassium-ATPase, alpha 1 polypeptide; sodium/potassium-transporting ATPase alpha-4 chain; Sodium/potassium-transporting ATPase subunit alpha-1; Sodium/potassium-transporting ATPase subunit alpha-4

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Gene Aliases: ATP1A1; ATP1A4; ATP1AL2; Atpa-1; BC010319; Nkaa1b

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UniProt ID: (Human) P05023, (Human) Q13733, (Rat) P06685, (Mouse) Q8VDN2, (Mouse) Q9WV27, (Rat) Q64541

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Entrez Gene ID: (Human) 476, (Human) 480, (Rat) 24211, (Mouse) 11928, (Mouse) 27222, (Rat) 29132

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Function(s)
sodium:potassium-exchanging ATPase activity protein binding ATP binding phosphatase activity protein kinase binding protein domain specific binding ankyrin binding potassium ion binding sodium ion binding ADP binding phosphatidylinositol 3-kinase binding chaperone binding steroid hormone binding metal ion binding nucleotide binding hydrolase activity
Process(es)
regulation of the force of heart contraction regulation of sodium ion transport potassium ion transport sodium ion transport cellular sodium ion homeostasis regulation of blood pressure potassium ion import energy coupled proton transmembrane transport, against electrochemical gradient dephosphorylation cellular potassium ion homeostasis negative regulation of glucocorticoid biosynthetic process sodium ion transmembrane transport sodium ion export from cell response to drug negative regulation of heart contraction positive regulation of heart contraction positive regulation of striated muscle contraction relaxation of cardiac muscle cardiac muscle contraction membrane hyperpolarization cellular response to mechanical stimulus cellular response to steroid hormone stimulus potassium ion transmembrane transport regulation of cardiac muscle cell contraction membrane repolarization response to glycoside establishment or maintenance of transmembrane electrochemical gradient ATP hydrolysis coupled proton transport ion transmembrane transport membrane repolarization during cardiac muscle cell action potential cell communication by electrical coupling involved in cardiac conduction regulation of cardiac conduction potassium ion import across plasma membrane transport ion transport spermatogenesis fertilization sperm motility regulation of cellular pH regulation of membrane potential metabolic process
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