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In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant mouse (rm) SorCS2 is observed and less than 1% cross-reactivity with recombinant human (rh) SorCS1 and rhSorCS3 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system.
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Protein Aliases: sortilin-related VPS10 domain containing receptor 2; VPS10 domain receptor protein; VPS10 domain-containing receptor SorCS2
Gene Aliases: KIAA1329; SORCS2
UniProt ID: (Human) Q96PQ0
Entrez Gene ID: (Human) 57537
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