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Invitrogen
Sorbitol Dehydrogenase Monoclonal Antibody (12B10G2)
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Sorbitol Dehydrogenase Antibody (MA5-49298) in IHC (P)
Immunohistochemistry analysis of Sorbitol Dehydrogenase in paraffin-embedded section of human SM fatty carcinoma of the left kidney tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. Samples were incubated with Sorbitol Dehydrogenase Monoclonal antibody (Product # MA5-49298) using a dilution of 2 μg/m... View More
Product Details
MA5-49298
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
12B10G2
Immunogen
E.coli-derived human Sorbitol Dehydrogenase/SORD recombinant protein (Position: N8-P357).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3074956
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human HepG2 whole cell, rat liver tissue tissue, rat kidney tissue, mouse liver tissue, mouse kidney tissue. IHC: human liver cancer tissue, human renal clear cell carcinoma tissue, human SM fatty carcinoma of the left kidney tissue, rat kidney tissue. Flow: U20S cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
Sorbitol dehydrogenase catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NADcofactor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (R,R)-butanediol dehydrogenase; epididymis secretory sperm binding protein Li 95n; L-iditol 2-dehydrogenase; Polyol dehydrogenase; RDH; Ribitol dehydrogenase; SDH; Sorbitol dehydrogenase; sorbitol dehydrogenase 1; SORD 1; XDH; Xylitol dehydrogenase
Gene Aliases: HEL-S-95n; Sdh-1; Sdh1; Sodh-1; SORD; SORD1
UniProt ID: (Human) Q00796, (Rat) P27867, (Mouse) Q64442
Entrez Gene ID: (Human) 6652, (Rat) 24788, (Mouse) 20322
sorbitol metabolic process
sorbitol catabolic process
response to osmotic stress
response to hormone
sperm motility
response to nutrient levels
response to drug
fructose biosynthetic process
response to cadmium ion
response to copper ion
L-xylitol catabolic process
L-xylitol metabolic process
oxidation-reduction process
glucose metabolic process
glucuronate catabolic process to xylulose 5-phosphate
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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