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Sorbitol dehydrogenase Polyclonal Antibody

Sorbitol dehydrogenase Antibody in Western Blot (WB)

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Sorbitol dehydrogenase Antibody (15881-1-AP) in WB

WB result of Sorbitol dehydrogenase antibody (Product # 15881-1-AP) 1:1,000, incubated at room temperature for 1.5 hours with sh-Control and sh-Sorbitol dehydrogenase transfected HeLa cells.

Sorbitol dehydrogenase Antibody in Immunoprecipitation (IP)

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Product Details

15881-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 4 publications 4 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Sorbitol dehydrogenase Fusion Protein Ag8651 (1-357 aa encoded by BC021085)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAAAAKPNN LSLVVHGPGD LRLENYPIPE PGPNEVLLRM HSVGICGSDV HYWEYGRIGN FIVKKPMVLG HEASGTVEKV GSSVKHLKPG DRVAIEPGAP RENDEFCKMG RYNLSPSIFF CATPPDDGNL CRFYKHNAAF CYKLPDNVTF EEGALIEPLS VGIHACRRGG VTLGHKVLVC GAGPIGMVTL LVAKAMGAAQ VVVTDLSATR LSKAKEIGAD LVLQISKESP QEIARKVEGQ LGCKPEVTIE CTGAEASIQA GIYATRSGGT LVLVGLGSEM TTVPLLHAAI REVDIKGVFR YCNTWPVAIS MLASKSVNVK PLVTHRFPLE KALEAFETFK KGLGLKIMLK CDPSDQNP (1-357 aa encoded by BC021085)

Target Information

Sorbitol dehydrogenase catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NADcofactor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Hepatocyte ferroptosis contributes to anti-tuberculosis drug-induced liver injury: Involvement of the HIF-1α/SLC7A11/GPx4 axis.

Chemico-biological interactions

Liu Y,Chen W,Cen Y,Zhao X,Chen Z,Liang Y,Huang Z,He X,Yang G

Mon May 01 00:00:00 UTC 2023

Exogenous H₂S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.

Journal of molecular medicine (Berlin, Germany)

Sun Y,Tian Z,Liu N,Zhang L,Gao Z,Sun X,Yu M,Wu J,Yang F,Zhao Y,Ren H,Chen H,Zhao D,Wang Y,Dong S,Xu C,Lu F,Zhang W

Sun Apr 01 00:00:00 UTC 2018

Exogenous H₂S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.

Journal of molecular medicine (Berlin, Germany)

Sun Y,Tian Z,Liu N,Zhang L,Gao Z,Sun X,Yu M,Wu J,Yang F,Zhao Y,Ren H,Chen H,Zhao D,Wang Y,Dong S,Xu C,Lu F,Zhang W

Sun Apr 01 00:00:00 UTC 2018

Protein profile screening: reduced expression of Sord in the mouse epididymis induced by nicotine inhibits tyrosine phosphorylation level in capacitated spermatozoa.

Reproduction (Cambridge, England)

Dai J,Xu W,Zhao X,Zhang M,Zhang D,Nie D,Bao M,Wang Z,Wang L,Qiao Z

Tue Mar 01 00:00:00 UTC 2016

Protein profile screening: reduced expression of Sord in the mouse epididymis induced by nicotine inhibits tyrosine phosphorylation level in capacitated spermatozoa.

Reproduction (Cambridge, England)

Dai J,Xu W,Zhao X,Zhang M,Zhang D,Nie D,Bao M,Wang Z,Wang L,Qiao Z

Tue Mar 01 00:00:00 UTC 2016

Protein profile screening: reduced expression of Sord in the mouse epididymis induced by nicotine inhibits tyrosine phosphorylation level in capacitated spermatozoa.

Reproduction (Cambridge, England)

Dai J,Xu W,Zhao X,Zhang M,Zhang D,Nie D,Bao M,Wang Z,Wang L,Qiao Z

Tue Mar 01 00:00:00 UTC 2016

Protein profile screening: reduced expression of Sord in the mouse epididymis induced by nicotine inhibits tyrosine phosphorylation level in capacitated spermatozoa.

Reproduction (Cambridge, England)

Dai J,Xu W,Zhao X,Zhang M,Zhang D,Nie D,Bao M,Wang Z,Wang L,Qiao Z

Tue Mar 01 00:00:00 UTC 2016

Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome.

Nature communications

Lanaspa MA,Ishimoto T,Li N,Cicerchi C,Orlicky DJ,Ruzycki P,Rivard C,Inaba S,Roncal-Jimenez CA,Bales ES,Diggle CP,Asipu A,Petrash JM,Kosugi T,Maruyama S,Sanchez-Lozada LG,McManaman JL,Bonthron DT,Sautin YY,Johnson RJ

Tue Apr 01 00:00:00 UTC 2014

Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome.

Nature communications

Tue Apr 01 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: (R,R)-butanediol dehydrogenase; epididymis secretory sperm binding protein Li 95n; L-iditol 2-dehydrogenase; Polyol dehydrogenase; RDH; Ribitol dehydrogenase; SDH; Sorbitol dehydrogenase; sorbitol dehydrogenase 1; SORD 1; XDH; Xylitol dehydrogenase

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Gene Aliases: HEL-S-95n; Sdh-1; Sdh1; Sodh-1; SORD; SORD1

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UniProt ID: (Human) Q00796, (Rat) P27867, (Mouse) Q64442

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Entrez Gene ID: (Human) 6652, (Rat) 24788, (Mouse) 20322

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Function(s)

L-iditol 2-dehydrogenase activity zinc ion binding carbohydrate binding identical protein binding D-xylulose reductase activity NAD binding oxidoreductase activity metal ion binding

Process(es)

sorbitol metabolic process sorbitol catabolic process response to osmotic stress response to hormone sperm motility response to nutrient levels response to drug fructose biosynthetic process response to cadmium ion response to copper ion L-xylitol catabolic process L-xylitol metabolic process oxidation-reduction process glucose metabolic process glucuronate catabolic process to xylulose 5-phosphate

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Sorbitol dehydrogenase Polyclonal Antibody

Sorbitol dehydrogenase Antibody (15881-1-AP) in WB

Product Details

15881-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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