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Osenses
Stargazin Polyclonal Antibody
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FIGURE: 1 / 10
Stargazin Antibody (OSC00107W-100UL) in IHC (P)
IHC-P on paraffin sections of rat cerebellum. The animal was perfused using Autoperfuser at a pressure of 130 mmHg with 300 mL 4% FA being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions; DAB chromogen: Candela DAB chromoge... View More
Product Details
OSC00107W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from mouse CACNG2 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The antigen is homologous in rat.
Specificity of this antibody: CACNG2.
Target Information
Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CaV gamma 2; MGC123981; MGC138502; MGC138504; Neuronal voltage-gated calcium channel gamma-2 subunit; Stargazin; TARP; TARP gamma 2; TARP gamma-2; Transmembrane AMPAR regulatory protein gamma-2; Voltage-dependent calcium channel gamma-2 subunit
Gene Aliases: AW060990; B230105C07Rik; B930041E13Rik; Cacng2; Ipr328; stargazer; stargazin; Stg; wag; waggler
UniProt ID: (Rat) Q71RJ2, (Mouse) O88602
Entrez Gene ID: (Rat) 84347, (Mouse) 12300
neuromuscular junction development
transmission of nerve impulse
regulation of ion transmembrane transport
regulation of membrane potential
neurological system process
membrane depolarization
membrane hyperpolarization
calcium ion transmembrane transport
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
transport
ion transport
calcium ion transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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