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Invitrogen
Stathmin 1 Monoclonal Antibody (SP49)
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FIGURE: 1 / 6
Stathmin 1 Antibody (MA5-16400) in ICC/IF
Immunofluorescence analysis of Stathmin 1 was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Stathmin 1 Monoclonal Antibody (SP49) (Product # MA5-16400) at 1:100 dilution in 0.1% BSA, incubated at 4 de... View More
Product Details
MA5-16400
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Monoclonal
Type
Antibody
Clone
SP49
Immunogen
Synthetic peptide derived from the internal region of human stathmin
Conjugate
Form
Liquid
Purification
Protein A/G
Storage buffer
PBS, pH 7.6, with 1% BSA
Contains
0.1% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2537919
Product Specific Information
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is tonsil or breast carcinoma.
Target Information
Stathmin 1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. Stathmin 1 is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: leukemia associated phosphoprotein p18; leukemia-associated cytosolic phosphoprotein stathmin; Leukemia-associated gene protein; Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; OTTHUMP00000008529; OTTHUMP00000008531; phosphoprotein 19; Phosphoprotein p19; pp17; pp19; Pr22 protein; Prosolin; Protein Pr22; RP1-125I3.5; Stathmin; stathmin 1 variant; stathmin 1/oncoprotein 18; STN1; testicular tissue protein Li 189; transmembrane protein C1orf215
Gene Aliases: 19k; C1orf215; Lag; LAP18; OP18; P18; P19; Pig; PP17; Pp18; PP19; PR22; prosolin; SMN; STMN1
UniProt ID: (Human) P16949, (Rat) P13668, (Mouse) P54227
Entrez Gene ID: (Human) 3925, (Rat) 29332, (Mouse) 16765
microtubule depolymerization
mitotic spindle organization
axonogenesis
brain development
response to virus
regulation of microtubule polymerization or depolymerization
negative regulation of microtubule polymerization
neuron projection development
intracellular signal transduction
positive regulation of cellular component movement
regulation of cytoskeleton organization
mitotic cytokinesis
signal transduction
multicellular organism development
nervous system development
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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