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Invitrogen
Streptococcus pyogenes Group A Polyclonal Antibody
Product Details
PA1-27089
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bacteria
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Killed Streptococcus pyogenes vaccine Strain J17A4.
Conjugate
Form
Liquid
Concentration
5.9 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_795456
Product Specific Information
PA1-27089 detects Streptococcus pyogenes Group A Carbohydrate from bacteria samples.
Target Information
Streptococcus pyogenes, also known as Group A Streptococcus (GAS), is a human-specific pathogen characterized by a multitude of virulence factors that contribute to its versatility in causing diseases. The genome of S. pyogenes reveals an expansive array of surface-expressed and secreted proteins that facilitate colonization, infection, and immune evasion. This includes adhesins, pili, and immune-modulatory proteins, among others. GAS is responsible for a broad spectrum of diseases such as pharyngitis, impetigo, cellulitis, and more severe invasive diseases like necrotizing fasciitis and streptococcal toxic shock syndrome. Furthermore, post-infection sequelae such as rheumatic fever and glomerulonephritis can arise due to host immune responses. The adaptation of GAS to diverse environmental niches within the human host through these genetic determinants highlights its evolutionary success and epidemiological impact.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: s pyogenes; S. pyogenes; streptococcus pyogenes
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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