Invitrogen

Substance P Polyclonal Antibody

1 Reference
View all (4) Substance P antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Product Details

PA5-106934

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:3,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
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Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human TAC1(Accession P20366), corresponding to amino acid residues D38-Y88.
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2854598

Product Specific Information

Antibody detects endogenous levels of total Substance P.

Target Information

Substance P (SP) is currently thought to be one of the most important neurotransmitters and neurotransmitters in the brain. It is an undecapeptide belonging to the tachykinin family, which consists of excitatory neuropeptides synthesised in neuronal and glial cells of the human central and peripheral nervous system. Substance P, Neurokinin A, Neuropeptide K, and Neuropeptide gamma are all generated by post-translation cleavage of the precursor Protachykinin-1. Substance P forms the major endogenous ligand for Neurokinin 1 Receptor. The pharmacology of Substance P has been associated with a number of neurological and psychiatric disorders, namely nociception, migraine, asthma, nausea, inflammatory bowel syndrome, urinary incontinence, anxiety and depression. It has also been linked to obesity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: MGC26719; neurokinin 1; neurokinin 2; neurokinin A; neurokinin alpha; neuromedin L; neuropeptide gamma; neuropeptide K; PPT; precursor 1; preprotachykinin; preprotachykinin A; protachykinin; Protachykinin-1; RAT TAC; substance K; substance P; Tachykinin (substance P, neurokinin A, neuropeptide K, neuropeptide gamma); tachykinin 1; tachykinin 2; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)

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Gene Aliases: 4930528L02Rik; Hs.2563; NK-1; NK1; NK2; NKA; NKNA; NPK; PPT-A; Ppt5fl; PPTA; PPTA3; RATPPTA3; SP; TAC; TAC1; TAC2

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UniProt ID: (Human) P20366, (Rat) P06767, (Mouse) P41539

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Entrez Gene ID: (Human) 6863, (Rat) 24806, (Mouse) 21333

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