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Synapsin III (SYN3) Antibody (ANR-017-200UL) in IHC (F)
Expression of Synapsins 3 in mouse and rat hippocampus - Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-Synapsins III (SYN3) Antibody (#ANR-017), (1:200), followed by goat Anti-rabbit-AlexaFluor-488. A. SYN3 staining (green) in mouse hippocampal CA3 region is detected in the mossy fiber terminal (MFT) region. B. In rat hippocampal dentate gyrus (DG) region, SYN3 immuno... View More
Product Details
ANR-017-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)RPPVQGRSTSQQGE, corresponding to amino acid residues 510-523 of rat Synapsin III, Extracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cN28H9.2 (synapsin III); synapsin 3; Synapsin III; synapsin IIIa; Synapsin-3
Gene Aliases: SYN3
UniProt ID: (Human) O14994, (Mouse) Q8JZP2, (Rat) O70441
Entrez Gene ID: (Human) 8224, (Mouse) 27204, (Rat) 29130
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