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Invitrogen
Synaptojanin 1 Monoclonal Antibody (AC1)
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FIGURE: 1 / 5
Synaptojanin 1 Antibody (MA3-936) in ICC/IF
Immunofluorescent analysis of Synaptojanin 1 (green) showing staining in the cytoplasm of U-87 MG cells (right) compared to a negative control without primary antibody (left). Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with a Synaptojanin 1 monoclonal antibody (Product # MA3-936) in ... View More
Product Details
MA3-936
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
AC1
Immunogen
Proline rich domain of a fusion protein comprising amino acids 1156-1286 of rat synaptojanin 1.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
PBS, ascites
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2201023
Product Specific Information
MA3-936 detects Synaptojanin 1 from rat and human samples.
MA3-936 has been successfully used in Western blotting, IHC (frozen), IP and ICC/IF procedures. By Western blot MA3-936 detects a band at 170 kDa representing Synaptojanin 1.
The MA3-936 immunogen is proline rich domain of a fusion protein comprising aa 1156-1286 of rat synaptojanin 1.
Target Information
Synaptojanin 1 is a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: inositol 5'-phosphatase (synaptojanin 1); inositol polyphosphate-5-phosphatase G; phosphoinositide 5-phosphatase; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1; synaptic inositol-1; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1; Synaptojanin-1; synaptojanin-1, polyphosphoinositide phosphatase
Gene Aliases: INPP5G; KIAA0910; PARK20; SYNJ1
UniProt ID: (Human) O43426, (Rat) Q62910
Entrez Gene ID: (Human) 8867, (Rat) 85238
nucleotide binding
RNA binding
phosphatidylinositol-3-phosphatase activity
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
phosphatidylinositol phosphate 5-phosphatase activity
phosphatidylinositol phosphate 4-phosphatase activity
phosphatidylinositol-4-phosphate phosphatase activity
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
inositol-1,4,5-trisphosphate 5-phosphatase activity
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
nucleic acid binding
protein binding
protein C-terminus binding
SH3 domain binding
protein complex binding
phosphoric ester hydrolase activity
neurotransmitter transport
brain development
learning
positive regulation of gliogenesis
synaptic vesicle priming
synaptic vesicle uncoating
response to retinoic acid
response to cytokine
phosphatidylinositol metabolic process
inositol phosphate dephosphorylation
phosphatidylinositol dephosphorylation
positive regulation of receptor-mediated endocytosis
synaptic vesicle endocytosis
synaptic vesicle transport
phosphatidylinositol biosynthetic process
phosphatidylinositol-3-phosphate biosynthetic process
inositol phosphate metabolic process
positive regulation of endosome organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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