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Synaptotagmin2 Polyclonal Antibody

Product Details

OSS00129G-500UG

Applications

Tested Dilution

Publications

Western Blot (WB)

10-50 µg/mL

Immunohistochemistry (IHC)

10-50 µg/mL

Miscellaneous PubMed (MISC)

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from the n-terminal region of human Synaptotagmin-2 (Synaptotagmin II, SytII, SYT2) conjugated to an immunogenic carrier protein was used as the antigen

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Purification

Ammonium sulfate precipitation

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

The peptide is homologous in rat and mouse.

Specificity of this antibody: SYTII.

Target Information

Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The transcriptional landscape of the mammalian genome.

Science (New York, N.Y.)

Carninci P,Kasukawa T,Katayama S,Gough J,Frith MC,Maeda N,Oyama R,Ravasi T,Lenhard B,Wells C,Kodzius R,Shimokawa K,Bajic VB,Brenner SE,Batalov S,Forrest AR,Zavolan M,Davis MJ,Wilming LG,Aidinis V,Allen JE,Ambesi-Impiombato A,Apweiler R,Aturaliya RN,Bailey TL,Bansal M,Baxter L,Beisel KW,Bersano T,Bono H,Chalk AM,Chiu KP,Choudhary V,Christoffels A,Clutterbuck DR,Crowe ML,Dalla E,Dalrymple BP,de Bono B,Della Gatta G,di Bernardo D,Down T,Engstrom P,Fagiolini M,Faulkner G,Fletcher CF,Fukushima T,Furuno M,Futaki S,Gariboldi M,Georgii-Hemming P,Gingeras TR,Gojobori T,Green RE,Gustincich S,Harbers M,Hayashi Y,Hensch TK,Hirokawa N,Hill D,Huminiecki L,Iacono M,Ikeo K,Iwama A,Ishikawa T,Jakt M,Kanapin A,Katoh M,Kawasawa Y,Kelso J,Kitamura H,Kitano H,Kollias G,Krishnan SP,Kruger A,Kummerfeld SK,Kurochkin IV,Lareau LF,Lazarevic D,Lipovich L,Liu J,Liuni S,McWilliam S,Madan Babu M,Madera M,Marchionni L,Matsuda H,Matsuzawa S,Miki H,Mignone F,Miyake S,Morris K,Mottagui-Tabar S,Mulder N,Nakano N,Nakauchi H,Ng P,Nilsson R,Nishiguchi S,Nishikawa S,Nori F,Ohara O,Okazaki Y,Orlando V,Pang KC,Pavan WJ,Pavesi G,Pesole G,Petrovsky N,Piazza S,Reed J,Reid JF,Ring BZ,Ringwald M,Rost B,Ruan Y,Salzberg SL,Sandelin A,Schneider C,Schönbach C,Sekiguchi K,Semple CA,Seno S,Sessa L,Sheng Y,Shibata Y,Shimada H,Shimada K,Silva D,Sinclair B,Sperling S,Stupka E,Sugiura K,Sultana R,Takenaka Y,Taki K,Tammoja K,Tan SL,Tang S,Taylor MS,Tegner J,Teichmann SA,Ueda HR,van Nimwegen E,Verardo R,Wei CL,Yagi K,Yamanishi H,Zabarovsky E,Zhu S,Zimmer A,Hide W,Bult C,Grimmond SM,Teasdale RD,Liu ET,Brusic V,Quackenbush J,Wahlestedt C,Mattick JS,Hume DA,Kai C,Sasaki D,Tomaru Y,Fukuda S,Kanamori-Katayama M,Suzuki M,Aoki J,Arakawa T,Iida J,Imamura K,Itoh M,Kato T,Kawaji H,Kawagashira N,Kawashima T,Kojima M,Kondo S,Konno H,Nakano K,Ninomiya N,Nishio T,Okada M,Plessy C,Shibata K,Shiraki T,Suzuki S,Tagami M,Waki K,Watahiki A,Okamura-Oho Y,Suzuki H,Kawai J,Hayashizaki Y

Fri Sep 02 00:00:00 UTC 2005

Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II.

The Journal of biological chemistry

Fukuda M,Aruga J,Niinobe M,Aimoto S,Mikoshiba K

Fri Nov 18 00:00:00 UTC 1994

Synaptotagmin II. A novel differentially distributed form of synaptotagmin.

The Journal of biological chemistry

Geppert M,Archer BT,Südhof TC

Thu Jul 25 00:00:00 UTC 1991

Bioinformatics

Protein Aliases: Inositol polyphosphate-binding protein; IP4-binding protein; synaptotagmin 2; Synaptotagmin II; Synaptotagmin-2; SytII

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Gene Aliases: CMS7; mKIAA4194; MYSPC; R74640; RATSYNII; SYNII; SYT2; SytII

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UniProt ID: (Human) Q8N9I0, (Rat) P29101, (Mouse) P46097

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Entrez Gene ID: (Human) 127833, (Rat) 24805, (Mouse) 20980

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Function(s)

calcium ion binding protein binding calcium-dependent phospholipid binding syntaxin binding clathrin binding inositol 1,3,4,5 tetrakisphosphate binding transporter activity metal ion binding

Process(es)

transport synaptic vesicle exocytosis vesicle fusion regulation of calcium ion-dependent exocytosis synaptic vesicle endocytosis calcium ion-regulated exocytosis of neurotransmitter positive regulation of dendrite extension neurotransmitter secretion

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Synaptotagmin2 Polyclonal Antibody

Product Details

OSS00129G-500UG

Western Blot (WB)

Immunohistochemistry (IHC)

Miscellaneous PubMed (MISC)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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