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Invitrogen
Syndecan 4 Polyclonal Antibody
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FIGURE: 1 / 4
Syndecan 4 Antibody (PA5-95950) in ICC/IF
Immunofluorescence analysis of SDC4 was performed using 70% confluent log phase A549 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Syndecan 4 Polyclonal Antibody (Product # PA5-95950) at 1:100 dilution in 0.1% BSA, incubated at 4 degrees Celsius... View More
Product Details
PA5-95950
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 19-145 of human SDC4 (NP_0029902)
Conjugate
Form
Liquid
Concentration
2.02 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2807752
Product Specific Information
Immunogen sequence: ESIRETEVID PQDLLEGRYF SGALPDDEDV VGPGQESDDF ELSGSGDLDD LEDSMIGPEV VHPLVPLDNH IPERAGSGSQ VPTEPKKLEE NEVIPKRISP VEESEDVSNK VSMSSTVQGS NIFERTE; Positive Samples: Mouse kidney; Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan 1 is a matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan 1 and Syndecan 3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan 2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan 4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Amphiglycan; MGC22217; ryudocan amphiglycan; Ryudocan core protein; SYND4; syndecan 4 (amphiglycan, ryudocan); syndecan proteoglycan 4; Syndecan-4
Gene Aliases: SDC4; SYND4
UniProt ID: (Human) P31431
Entrez Gene ID: (Human) 6385
retinoid metabolic process
ureteric bud development
neural tube closure
glycosaminoglycan biosynthetic process
glycosaminoglycan catabolic process
signal transduction
regulation of fibroblast migration
cell migration
glycosaminoglycan metabolic process
wound healing
positive regulation of protein kinase activity
positive regulation of stress fiber assembly
positive regulation of focal adhesion assembly
inner ear receptor stereocilium organization
positive regulation of exosomal secretion
positive regulation of extracellular exosome assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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