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Invitrogen
Synip Polyclonal Antibody
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Product Details
PA5-45759
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human STXBP4 (aa 72-121).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2607139
Product Specific Information
Peptide sequence: SVNKESMIGV SFEEAKSIIT GAKLRLESAW EIAFIRQKSD NIQPENLSCT
Sequence homology: Human: 100%
Target Information
STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ16496; MGC149829; MGC50337; STX4-interacting protein; syntaxin 4 interacting protein; Syntaxin 4-interacting protein; Syntaxin-binding protein 4
Gene Aliases: STXBP4; Synip
UniProt ID: (Human) Q6ZWJ1
Entrez Gene ID: (Human) 252983
protein targeting
cellular response to DNA damage stimulus
insulin receptor signaling pathway
positive regulation of keratinocyte proliferation
glucose transport
protein stabilization
regulation of insulin secretion involved in cellular response to glucose stimulus
positive regulation of cell cycle G1/S phase transition
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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